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Patil, Deepak B.
- Analysis of the Constituents of Urinary Calculi of Dog Using Various Scientific Techniques
Abstract Views :243 |
PDF Views:86
Authors
Affiliations
1 Analytical Discipline and Centralized Instrument Facility, CSIR-Central Salt and Marine Chemicals Research Institute, G.B. Marg, Bhavnagar 364 002, IN
2 College of Veterinary Science and Animal Husbandry, Anand Agricultural University, Anand 388 001, IN
1 Analytical Discipline and Centralized Instrument Facility, CSIR-Central Salt and Marine Chemicals Research Institute, G.B. Marg, Bhavnagar 364 002, IN
2 College of Veterinary Science and Animal Husbandry, Anand Agricultural University, Anand 388 001, IN
Source
Current Science, Vol 110, No 5 (2016), Pagination: 863-867Abstract
Analytical techniques have been used to determine constituents of urinary stones of different breeds of dogs obtained from the College of Veterinary Science and Animal Husbandry, Anand Agricultural University, India. Analysis by powder XRD, FTIR and TGA suggests the presence of pure phases such as calcium oxalate monohydrate, struvite and calcium carbonate, and also mixed phases containing calcium oxalate hydrate, struvite, whewellite and weddellite in the urinary calculi. The morphology of the constituents has been studied by optical and scanning electron microscope. Activation energy and order of reaction for thermal elimination of H2O, CO and CO2 have been determined.Keywords
Analytical Techniques, Dogs, Powder X-Ray Diffraction, Urinary Calculi.Full Text
- Identification of Genetic Variants in PDC, RHO, PDE6A and PDE6B in Dogs with Progressive Retinal Atrophy
Abstract Views :209 |
PDF Views:77
Authors
Dipal Y. Pandya
1,
Divyesh N. Kelawala
2,
Namrata V. Patel
1,
Tejas M. Shah
1,
Anand B. Patel
1,
Nidhi R. Parmar
1,
Bhaskar Reddy
1,
Deepak B. Patil
2,
Chaitanya G. Joshi
1
Affiliations
1 Department of Animal Biotechnology, College of Veterinary Science and Animal Husbandry, Anand Agricultural University, Anand 388 001, IN
2 Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Anand Agricultural University, Anand 388 001, IN
1 Department of Animal Biotechnology, College of Veterinary Science and Animal Husbandry, Anand Agricultural University, Anand 388 001, IN
2 Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Anand Agricultural University, Anand 388 001, IN
Source
Current Science, Vol 111, No 10 (2016), Pagination: 1640-1648Abstract
The progressive retinal atrophy (PRA) is an inherited eye disease and characterized by progressive retinal degeneration which leads to impaired vision in dogs. Using targeted next generation sequencing of nine PRA cases and six controls, we have identified SNPs in PDC, PDE6A and PDE6B, which were not previously associated with PRA. The gene in which the highest mutations found was PDE6A (113 and 104 SNPs), followed by PDE6B, PDC and RHO in all dog breeds and Spitz-only respectively. Five SNPs identified in PDC gene of Spitz-only breed showed significant association with PRA. However, no pathogenetically relevant mutations were found in RHO gene for PRA. The SNP in PDE6B chr3: 91763017 (G/A) in Spitz-only breed, and PDE6A chr4: 5912574 (T/C) and PDC chr7: 19511750 (T/A) were associated with PRA in the breeds of dog studied. Our results show that PRA is genetically heterogeneous and is caused by multiple, distinct mutations.Keywords
Genome-Wide Association, Next Generation Sequencing, Progressive Retinal Atrophy, Single Nucleotide Polymorphisms.Full Text
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